Here is a reprint of site location considerations from www.toolkit.com/small_business_guide. Some of these factors need to be assessed during an on-site visit, but a majority of them can only be discovered using geospatial information analysis.
An important factor in selecting a location is that you keep a long-term perspective. Site selection can be a big investment. Choosing the right site now can avoid the costs of relocation in the future.
Here are some factors that you should consider in making your site decision:
Access to public transportation
Availability of inventory and supplies
Availability of utilities
Availability of workforce
Availability of physical plants
Community services and amenities
Cost of physical plant
Location of competitors
Proximity to markets
Suitability of location for future expansion
Wage scales in the locality